WYE MILLS, Md. (WJZ) — All lanes reopened on Route 50 after a serious crash, Maryland State Highway Administration reports.

The four-vehicle crash was just prior to MD-404 in Talbot County.

A 34-year-old woman was driving when she hit a car setting off a chain reaction crash involving two other vehicles.

Four people were taken to Shock Trauma.

Although lanes are reopened, delays should be expected in the area.

The driver was charged with negligent driving.

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