FREDERICK, Md. (AP) — Pharmaceutical giant AstraZeneca says it will bring 300 new jobs to Maryland with a $200 million project to expand a Frederick manufacturing center.

The Frederick News-Post reports the company said Friday in a news release that the expansion will allow the company to increase production at its MedImmune facility. The Gaithersburg-based MedImmune is a subsidiary of the London-based AstraZeneca.

Work to enlarge the manufacturing center by 40,000 square feet is expected to begin in December and finish in 2017. A company spokeswoman says a majority of the 300 manufacturing, laboratory and administrative positions will be filled by 2017.

The state of Maryland agreed to provide the company with a $1.5 million loan to encourage the expansion project.

(Copyright 2014 by The Associated Press. All Rights Reserved.)

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