By Madeline Holcombe, CNN

(CNN) — After a week of dauntingly high numbers in all parameters of the pandemic, the US has reached another sobering mark: its highest number of new daily Covid-19 cases since the virus entered the country.

On Saturday, there were 126,742 new coronavirus cases, according to Johns Hopkins University.

The record marked the fourth day last week that new cases totaled more than 100,000 and the third day in a row that new cases topped more than 120,000, according to a CNN analysis.

The fall resurgence has brought regular records in cases, people hospitalized and daily deaths — and experts are encouraging measures to mitigate the spread as they warn that the numbers may continue to climb in coming weeks.

“We’re going to see these case numbers really start to explode,” former US Food and Drug Administration Commissioner Dr. Scott Gottlieb told CNBC on Friday.

The virus can be dealt with by targeting mitigation state by state, he said, but the US is not doing that currently, and the lack of intervention could build up for the future, spelling trouble for December and January, he said.

“It’s not just the cases; it’s the hospitalizations as well. That’s really the number to watch: 53,000 people hospitalized, 10,500 people in ICUs. That’s a lot, and it’s growing very quickly.”

Sixteen states reported record high Covid-19 hospitalizations Friday, according to the Covid Tracking Project, and 22 states have reported at least one record high day of coronavirus hospitalizations during November, so far. Since the pandemic started, more than 9.8 million people have been infected and 237,192 people have died of the virus, according to Johns Hopkins.

On Sunday morning, the global number of cases topped 50 million, with the United States, India, Brazil and Russia, in that order, the hardest hit, composing more than half the cases, Johns Hopkins reports.

Fauci: stick with science, not politics

The pandemic will soon become the primary concern of President-elect Joe Biden. He plans to announce a 12-person coronavirus task force Monday, two sources with knowledge of the announcement told CNN.

Biden’s task force will be headed by three co-chairs, including former Surgeon General Dr. Vivek Murthy, former Food and Drug Administration Commissioner Dr. David Kessler and Yale University’s Dr. Marcella Nunez-Smith.

In a virtual event with the American Medical Association on Saturday, Dr. Anthony Fauci, director of the Institute for Allergy and Infectious Diseases, advised physicians in leadership roles to stick with science, evidence and data when it comes to making coronavirus recommendations.

“Stay completely apolitical. Don’t get involved in any of the political aspects, and just focus on what your job is as a scientist and a physician,” Fauci said. “You do that, you’ll be fine.”

Health experts have been working to combat skepticism around coronavirus vaccines and recommendations after being at odds at times with political leaders.

‘Age, experience and better drugs’ impact death rate

Though the death toll has climbed, the rate of cases that have resulted in fatalities has seemingly decreased, and Fauci said that is due to “age, experience and better drugs.”

As with all diseases, health professionals learn more about the virus as it went on, including when to put people on ventilators, Fauci said Saturday.

“We just get better at treating people,” he said. “You (know) what works. You know what doesn’t work, including just fundamental, nonpharmacological approaches.”

The use of treatments that can help people, such as dexamethasone and remdesivir, has also further developed, he said.

Also impacting the death rate are the college students going back to school and being infected more, he said. Those getting infected now compared with the spring “is almost a decade difference of being younger now.”

“Ultimately, they’re going to wind up infecting people in the community, but they’re the ones that are sort of driving the infection,” Fauci said.

Covid symptoms last ‘well beyond’ expectation

As researchers learn more about the virus, they’re noticing that the impacts can drag on, Fauci said.

Some patients have reported symptoms lasting even after they have tested negative from a coronavirus infection.

“We do know for absolutely certain that there is a post-Covid-19 syndrome — referred to sometimes as long Covid, chronic Covid, long haulers,” Fauci said during the AMA event.

“We’re seeing variable percentages, and anywhere from 25 to 35% or more have lingering symptoms — well beyond what you’d expect post any viral syndrome, like influenza and others,” he said.

Symptoms include fatigue, shortness of breath, muscle aches, sleep disturbances and what is referred to as “brain fog.”

“So, there’s no doubt that it’s going on, that (it) can last anywhere from weeks to months,” he said, adding that it could be longer, but that isn’t known because the novel virus was discovered less than a year ago.

The-CNN-Wire
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